Proteomic Analysis of Urine Exosomes Reveals Renal Tubule Response to Leptospiral Colonization in Experimentally Infected Rats

BACKGROUND: Infectious Leptospira colonize the kidneys of reservoir (e.g. rats) and accidental hosts such as humans. The renal response to persistent leptospiral colonization, as measured by urinary protein biosignatures, has not been systematically studied. Urinary exosomes--bioactive membrane-boun...

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Detalles Bibliográficos
Autores principales: RamachandraRao, Satish P., Matthias, Michael A., Mondrogon, Chanthel-Kokoy, Aghania, Eamon, Park, Cathleen, Kong, Casey, Ishaya, Michelle, Madrigal, Assael, Horng, Jennifer, Khoshaba, Roni, Bounkhoun, Anousone, Basilico, Fabrizio, De Palma, Antonella, Agresta, Anna Maria, Awdishu, Linda, Naviaux, Robert K., Vinetz, Joseph M., Mauri, Pierluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368819/
https://www.ncbi.nlm.nih.gov/pubmed/25793258
http://dx.doi.org/10.1371/journal.pntd.0003640

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