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Transcriptionally Active Regions Are the Preferred Targets for Chromosomal HPV Integration in Cervical Carcinogenesis

Integration of human papillomavirus (HPV) into the host genome is regarded as a determining event in cervical carcinogenesis. However, the exact mechanism for integration, and the role of integration in stimulating cancer progression, is not fully characterized. Although integration sites are report...

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Detalles Bibliográficos
Autores principales: Christiansen, Irene Kraus, Sandve, Geir Kjetil, Schmitz, Martina, Dürst, Matthias, Hovig, Eivind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368827/
https://www.ncbi.nlm.nih.gov/pubmed/25793388
http://dx.doi.org/10.1371/journal.pone.0119566

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