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Transcriptionally Active Regions Are the Preferred Targets for Chromosomal HPV Integration in Cervical Carcinogenesis
Integration of human papillomavirus (HPV) into the host genome is regarded as a determining event in cervical carcinogenesis. However, the exact mechanism for integration, and the role of integration in stimulating cancer progression, is not fully characterized. Although integration sites are report...
Autores principales: | Christiansen, Irene Kraus, Sandve, Geir Kjetil, Schmitz, Martina, Dürst, Matthias, Hovig, Eivind |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368827/ https://www.ncbi.nlm.nih.gov/pubmed/25793388 http://dx.doi.org/10.1371/journal.pone.0119566 |
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