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REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous infusions of granulocyte colony-stimulating factor (GCSF) mobilised CD133+ bone marrow stem cells in patients with cirrhosis. A study protocol for a randomised controlled trial

INTRODUCTION: Liver disease mortality and morbidity are rapidly rising and liver transplantation is limited by organ availability. Small scale human studies have shown that stem cell therapy is safe and feasible and has suggested clinical benefit. No published studies have yet examined the effect of...

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Detalles Bibliográficos
Autores principales: King, A, Barton, D, Beard, H A, Than, N, Moore, J, Corbett, C, Thomas, J, Guo, K, Guha, I, Hollyman, D, Stocken, D, Yap, C, Fox, R, Forbes, S J, Newsome, P N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368910/
https://www.ncbi.nlm.nih.gov/pubmed/25795699
http://dx.doi.org/10.1136/bmjopen-2015-007700