Combination of cyclophosphamide and double-stranded DNA demonstrates synergistic toxicity against established xenografts

BACKGROUND: Extracellular double-stranded DNA participates in various processes in an organism. Here we report the suppressive effects of fragmented human double-stranded DNA along or in combination with cyclophosphamide on solid and ascites grafts of mouse Krebs-2 tumor cells and DNA preparation on...

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Detalles Bibliográficos
Autores principales: Alyamkina, Ekaterina A, Nikolin, Valeriy P, Popova, Nelly A, Minkevich, Alexandra M, Kozel, Artem V, Dolgova, Evgenia V, Efremov, Yaroslav R, Bayborodin, Sergey I, Andrushkevich, Oleg M, Taranov, Oleg S, Omigov, Vladimir V, Rogachev, Vladimir A, Proskurina, Anastasia S, Vereschagin, Evgeniy I, Kiseleva, Elena V, Zhukova, Maria V, Ostanin, Alexandr A, Chernykh, Elena R, Bogachev, Sergey S, Shurdov, Mikhail A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369063/
https://www.ncbi.nlm.nih.gov/pubmed/25798073
http://dx.doi.org/10.1186/s12935-015-0180-6

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