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Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report

Study Design Case report. Objective To describe a very rare case of an immunocompetent man who underwent surgery for thoracic spondylodiscitis caused by methicillin-resistant Staphylococcus aureus (MRSA) that developed as a superinfection of a pulmonary tuberculous granuloma. Methods Posterior decom...

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Autores principales: Donnarumma, Pasquale, Tarantino, Roberto, Palmarini, Valeria, De Giacomo, Tiziano, Delfini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369207/
https://www.ncbi.nlm.nih.gov/pubmed/25844289
http://dx.doi.org/10.1055/s-0034-1390009
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author Donnarumma, Pasquale
Tarantino, Roberto
Palmarini, Valeria
De Giacomo, Tiziano
Delfini, Roberto
author_facet Donnarumma, Pasquale
Tarantino, Roberto
Palmarini, Valeria
De Giacomo, Tiziano
Delfini, Roberto
author_sort Donnarumma, Pasquale
collection PubMed
description Study Design Case report. Objective To describe a very rare case of an immunocompetent man who underwent surgery for thoracic spondylodiscitis caused by methicillin-resistant Staphylococcus aureus (MRSA) that developed as a superinfection of a pulmonary tuberculous granuloma. Methods Posterior decompression and pedicle screw vertebral fixation were followed by T5–T6 anterior somatotomy with implant of an expandable mesh and lateral plating as symptoms worsened. During the anterior approach, an atypical resection of the left lower lobe was also performed. Results A tuberculous granuloma was detected on histology. Ziehl-Neelsen stain confirmed the diagnosis. Culture also detected MRSA. Conclusions Early medical management is the first choice for spondylodiscitis to eradicate the infection and alleviate pain. Immobilization of the affected spine segments can protect the patient from vertebral collapse and from the appearance of neurologic deficits. Surgery is suggested if there are compressive effects on the spinal cord, spinal epidural abscess, vertebral collapse, and deformity. We decided to remove the abscess and to restore the anterior column using an anterior approach. Moreover, in this case, an anterior approach allowed us to identify the etiology of the lesion and to determine the best chemotherapy regimen.
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spelling pubmed-43692072015-04-03 Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report Donnarumma, Pasquale Tarantino, Roberto Palmarini, Valeria De Giacomo, Tiziano Delfini, Roberto Global Spine J Article Study Design Case report. Objective To describe a very rare case of an immunocompetent man who underwent surgery for thoracic spondylodiscitis caused by methicillin-resistant Staphylococcus aureus (MRSA) that developed as a superinfection of a pulmonary tuberculous granuloma. Methods Posterior decompression and pedicle screw vertebral fixation were followed by T5–T6 anterior somatotomy with implant of an expandable mesh and lateral plating as symptoms worsened. During the anterior approach, an atypical resection of the left lower lobe was also performed. Results A tuberculous granuloma was detected on histology. Ziehl-Neelsen stain confirmed the diagnosis. Culture also detected MRSA. Conclusions Early medical management is the first choice for spondylodiscitis to eradicate the infection and alleviate pain. Immobilization of the affected spine segments can protect the patient from vertebral collapse and from the appearance of neurologic deficits. Surgery is suggested if there are compressive effects on the spinal cord, spinal epidural abscess, vertebral collapse, and deformity. We decided to remove the abscess and to restore the anterior column using an anterior approach. Moreover, in this case, an anterior approach allowed us to identify the etiology of the lesion and to determine the best chemotherapy regimen. Georg Thieme Verlag KG 2014-08-30 2015-04 /pmc/articles/PMC4369207/ /pubmed/25844289 http://dx.doi.org/10.1055/s-0034-1390009 Text en © Thieme Medical Publishers
spellingShingle Article
Donnarumma, Pasquale
Tarantino, Roberto
Palmarini, Valeria
De Giacomo, Tiziano
Delfini, Roberto
Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title_full Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title_fullStr Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title_full_unstemmed Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title_short Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
title_sort thoracic spondylodiscitis caused by methicillin-resistant staphylococcus aureus as a superinfection of pulmonary tuberculous granuloma in an immunocompetent patient: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369207/
https://www.ncbi.nlm.nih.gov/pubmed/25844289
http://dx.doi.org/10.1055/s-0034-1390009
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