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Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature
Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clini...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369234/ https://www.ncbi.nlm.nih.gov/pubmed/25802700 |
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author | Aznab, Mozaffar Kamalian, Naser Beiki, Omid Naleini, Farhad |
author_facet | Aznab, Mozaffar Kamalian, Naser Beiki, Omid Naleini, Farhad |
author_sort | Aznab, Mozaffar |
collection | PubMed |
description | Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clinical and radiologic findings, its diagnosis might be challenging. It might be more commonly found in patients with specific cytogenetic abnormalities, particularly with the t (8; 21) translocation and less frequently the inv (16) type. We report a case of GS in a 62 years old man without particular previous pathologies, which brutally presented as an ascites and generalized edema. The laparoscopy showed involvement of greater omentum and peritoneum. The histologic examination of greater omentum showed granulocytic sarcoma. The bone marrow aspiration was normal. We started treatment of patient by standard acute myeloid leukemia's chemotherapy. |
format | Online Article Text |
id | pubmed-4369234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-43692342015-03-23 Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature Aznab, Mozaffar Kamalian, Naser Beiki, Omid Naleini, Farhad Int J Hematol Oncol Stem Cell Res Case Report Myeloid sarcoma or granulocytic sarcoma (GS) is a rare disease with poor prognosis. It is characterized by the occurrence of tumor masses at an extra-medullary tissue. It is composed of myeloblastic cells and usually occurs in association with acute myeloid leukemia. Because of its nonspecific clinical and radiologic findings, its diagnosis might be challenging. It might be more commonly found in patients with specific cytogenetic abnormalities, particularly with the t (8; 21) translocation and less frequently the inv (16) type. We report a case of GS in a 62 years old man without particular previous pathologies, which brutally presented as an ascites and generalized edema. The laparoscopy showed involvement of greater omentum and peritoneum. The histologic examination of greater omentum showed granulocytic sarcoma. The bone marrow aspiration was normal. We started treatment of patient by standard acute myeloid leukemia's chemotherapy. Tehran University of Medical Sciences 2015-01-01 /pmc/articles/PMC4369234/ /pubmed/25802700 Text en © 2013 Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Case Report Aznab, Mozaffar Kamalian, Naser Beiki, Omid Naleini, Farhad Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title | Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title_full | Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title_fullStr | Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title_full_unstemmed | Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title_short | Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature |
title_sort | myeloid sarcoma of the peritoneum at older ages: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369234/ https://www.ncbi.nlm.nih.gov/pubmed/25802700 |
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