High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures

Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and...

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Detalles Bibliográficos
Autores principales: Boyer, Anne E., Gallegos-Candela, Maribel, Quinn, Conrad P., Woolfitt, Adrian R., Brumlow, Judith O., Isbell, Katherine, Hoffmaster, Alex R., Lins, Renato C., Barr, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://www.ncbi.nlm.nih.gov/pubmed/25673244
http://dx.doi.org/10.1007/s00216-015-8509-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://www.ncbi.nlm.nih.gov/pubmed/25673244
http://dx.doi.org/10.1007/s00216-015-8509-5

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