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Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma
Medulloblastoma (MB) is a highly malignant brain tumor that occurs primarily in children. Although surgery, radiation and high-dose chemotherapy have led to increased survival, many MB patients still die from their disease, and patients who survive suffer severe long-term side effects as a consequen...
Autores principales: | Brun, Sonja N., Markant, Shirley L., Esparza, Lourdes A., Garcia, Guillermina, Terry, David, Huang, Jen-Ming, Pavlyukov, Marat S., Li, Xiao-Nan, Grant, Gerald A., Crawford, John R., Levy, Michael L., Conway, Edward M., Smith, Layton H., Nakano, Ichiro, Berezov, Alan, Greene, Mark I., Wang, Qiang, Wechsler-Reya, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369477/ https://www.ncbi.nlm.nih.gov/pubmed/25241898 http://dx.doi.org/10.1038/onc.2014.304 |
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