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Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a
Progesterone (P4) has emerged as an important hormone regulating mammary stem cell populations. In breast cancer, P4 and synthetic analogs increase the number of stem-like cells within luminal estrogen receptor (ER) and progesterone receptor (PR) positive breast cancers. These cells gain expression...
Autores principales: | Finlay-Schultz, Jessica, Cittelly, Diana M., Hendricks, Peter, Patel, Purvi, Kabos, Peter, Jacobsen, Britta M., Richer, Jennifer K., Sartorius, Carol A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369481/ https://www.ncbi.nlm.nih.gov/pubmed/25241899 http://dx.doi.org/10.1038/onc.2014.298 |
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