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The transcriptional response to tumorigenic polarity loss in Drosophila

Loss of polarity correlates with progression of epithelial cancers, but how plasma membrane misorganization drives oncogenic transcriptional events remains unclear. The polarity regulators of the Drosophila Scribble (Scrib) module are potent tumor suppressors and provide a model for mechanistic inve...

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Detalles Bibliográficos
Autores principales:	Bunker, Brandon D, Nellimoottil, Tittu T, Boileau, Ryan M, Classen, Anne K, Bilder, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369581/ https://www.ncbi.nlm.nih.gov/pubmed/25719210 http://dx.doi.org/10.7554/eLife.03189

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