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Genetic determinants for methotrexate response in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIAs) is the most common chronic rheumatic disease of childhood and is an important cause of disability. The folic acid analog methotrexate is the first choice disease-modifying anti-rheumatic drug in this disease, however, 35–45% of patients fail to respond. Molecular...

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Detalles Bibliográficos
Autores principales:	Pastore, Serena, Stocco, Gabriele, Favretto, Diego, De Iudicibus, Sara, Taddio, Andrea, d’Adamo, Pio, Malusà, Noelia, Addobbati, Riccardo, Decorti, Giuliana, Lepore, Loredana, Ventura, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369651/ https://www.ncbi.nlm.nih.gov/pubmed/25852556 http://dx.doi.org/10.3389/fphar.2015.00052

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