Cargando…

The Hypoxia-Inducible Factor Pathway in Adipocytes: The Role of HIF-2 in Adipose Inflammation and Hypertrophic Cardiomyopathy

Under obese conditions, adipose tissue can become oxygen-deficient or hypoxic. Extensive work has been done using various diet-induced obesity models to demonstrate an important role of hypoxia-induced signaling in adipose tissue and its impact on adipose functions related to adipogenesis, insulin s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Qun, Yun, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369725/ https://www.ncbi.nlm.nih.gov/pubmed/25852648 http://dx.doi.org/10.3389/fendo.2015.00039

Ejemplares similares

The Role of Fat Reducing Agents on Adipocyte Death and Adipose Tissue Inflammation
por: Muskat, Ahava, et al.
Publicado: (2022)

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
por: Wang, Bohan, et al.
Publicado: (2007)

Oxygen Deprivation and the Cellular Response to Hypoxia in Adipocytes – Perspectives on White and Brown Adipose Tissues in Obesity
por: Trayhurn, Paul, et al.
Publicado: (2015)

Cooperation between HMGA1 and HIF-1 Contributes to Hypoxia-Induced VEGF and Visfatin Gene Expression in 3T3-L1 Adipocytes
por: Messineo, Sebastiano, et al.
Publicado: (2016)

Hypoxia-driven metabolic reprogramming of adipocytes fuels cancer cell proliferation
por: Aird, R., et al.
Publicado: (2022)

Association Between Thyroid Dysfunction and Incidence of Atrial Fibrillation in Patients With Hypertrophic Obstructive Cardiomyopathy
por: Meng, Xiangbin, et al.
Publicado: (2022)

Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
por: Zhao, Lidan, et al.
Publicado: (2023)

NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue
por: Bové, María, et al.
Publicado: (2021)

Differentiation of Human Adipose-Derived Stem Cells into “Brite” (Brown-in-White) Adipocytes
por: Pisani, Didier F., et al.
Publicado: (2011)

Peritumoral adipose tissue promotes lipolysis and white adipocytes browning by paracrine action
por: Pagnotta, Priscila, et al.
Publicado: (2023)

Mechanotransduction regulates inflammation responses of epicardial adipocytes in cardiovascular diseases
por: Liu, Xiaoliang, et al.
Publicado: (2022)

The Role of Adipocyte Precursors in Development and Obesity
por: Ying, Tammy, et al.
Publicado: (2021)

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis
por: Richard, Allison J., et al.
Publicado: (2022)

TGF-β/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue
por: Yadav, Hariom, et al.
Publicado: (2012)

Role of Inflammation in Vascular Disease-Related Perivascular Adipose Tissue Dysfunction
por: Chen, Yaozhi, et al.
Publicado: (2021)

MDM2 Regulation of HIF Signaling Causes Microvascular Dysfunction in Hypertrophic Cardiomyopathy
por: Shridhar, Puneeth, et al.
Publicado: (2023)

Role of Ubiquilins for Brown Adipocyte Proteostasis and Thermogenesis
por: Muley, Carolin, et al.
Publicado: (2021)

Distinct inflammatory signatures of upper and lower body adipose tissue and adipocytes in women with normal weight or obesity
por: Lempesis, Ioannis G., et al.
Publicado: (2023)

Angiotensinogen Gene Silencing Reduces Markers of Lipid Accumulation and Inflammation in Cultured Adipocytes
por: Carroll, Wenting X., et al.
Publicado: (2013)

Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation
por: Ren, Yakun, et al.
Publicado: (2022)

Activation of Hypoxia‐Inducible Factor‐2 in Adipocytes Results in Pathological Cardiac Hypertrophy
por: Lin, Qun, et al.
Publicado: (2013)

Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD(+)/SIRT1 axis
por: Wu, Keke, et al.
Publicado: (2023)

Role of Dapagliflozin and Liraglutide on Diabetes-Induced Cardiomyopathy in Rats: Implication of Oxidative Stress, Inflammation, and Apoptosis
por: El-Shafey, Mohamed, et al.
Publicado: (2022)

Melatonin Supplementation Decreases Hypertrophic Obesity and Inflammation Induced by High-Fat Diet in Mice
por: de Farias, Talita da Silva Mendes, et al.
Publicado: (2019)

THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue
por: Keuper, Michaela, et al.
Publicado: (2011)

YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity
por: Lee, Gwan-Jun, et al.
Publicado: (2022)

Adipocyte dysfunction promotes lung inflammation and aberrant repair: a potential target of COPD
por: Zhang, Si-jin, et al.
Publicado: (2023)

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
por: Ali, Mohamed M., et al.
Publicado: (2020)

Keep Hypoxia-Inducible Factor α and Stay Cool: Adipocyte HIFα regulates thermogenic execution.
por: Han, Ji Seul
Publicado: (2022)

Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice
por: Gavin, Kathleen M., et al.
Publicado: (2022)

Roles of estrogens, estrogen-like compounds, and endocrine disruptors in adipocytes
por: Lizcano, Fernando
Publicado: (2022)

Distinct Metabolism of Bone Marrow Adipocytes and their Role in Bone Metastasis
por: Li, Yixuan, et al.
Publicado: (2022)

Identification and analysis of key hypoxia- and immune-related genes in hypertrophic cardiomyopathy
por: Yu, Haozhen, et al.
Publicado: (2023)

The Circulatory and Metabolic Responses to Hypoxia in Humans – With Special Reference to Adipose Tissue Physiology and Obesity
por: Heinonen, Ilkka H. A., et al.
Publicado: (2016)

Transcriptional Pathways in cPGI(2)-Induced Adipocyte Progenitor Activation for Browning
por: Bayindir, Irem, et al.
Publicado: (2015)

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes
por: Perugini, Jessica, et al.
Publicado: (2019)

Role of inflammation in the pathogenesis of hypertrophic cardiomyopathy: a T2-mapping CMR study
por: Ismail, Tevfik F, et al.
Publicado: (2012)

Linking Adiposity to Interstitial Lung Disease: The Role of the Dysfunctional Adipocyte and Inflammation
por: Macklin, Michael, et al.
Publicado: (2023)

The role of echocardiography in management of hypertrophic cardiomyopathy
por: Haland, Trine F., et al.
Publicado: (2019)

Survival and prognostic factors in hypertrophic cardiomyopathy: a meta-analysis
por: Liu, Qun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_10jjdqrra9pdumpjojtl1spgsc