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Design of a PDZbody, a bivalent binder of the E6 protein from human papillomavirus

Chronic infection by high risk human papillomavirus (HPV) strains may lead to cancer. Expression of the two viral oncoproteins E6 and E7 is largely responsible for immortalization of infected cells. The HPV E6 is a small (approximately 150 residues) two domain protein that interacts with a number of...

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Detalles Bibliográficos
Autores principales:	Karlsson, O. Andreas, Ramirez, Juan, Öberg, Daniel, Malmqvist, Tony, Engström, Åke, Friberg, Maria, Chi, Celestine N., Widersten, Mikael, Travé, Gilles, Nilsson, Mikael T. I., Jemth, Per
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369733/ https://www.ncbi.nlm.nih.gov/pubmed/25797137 http://dx.doi.org/10.1038/srep09382

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