ASPP2 enhances Oxaliplatin (L-OHP)-induced colorectal cancer cell apoptosis in a p53-independent manner by inhibiting cell autophagy

Inactivation of p53-mediated cell death pathways is a central component of cancer progression. ASPP2 (apoptosis stimulated protein of p53-2) is a p53 binding protein that specially stimulates pro-apoptosis function of p53. Down-regulation of ASPP2 is observed in many human cancers and is associated...

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Detalles Bibliográficos
Autores principales: Shi, Ying, Han, Yue, Xie, Fang, Wang, Anna, Feng, Xiaokun, Li, Ning, Guo, Hongliang, Chen, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369811/
https://www.ncbi.nlm.nih.gov/pubmed/25534115
http://dx.doi.org/10.1111/jcmm.12435

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