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Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy

Cyclins/retinoblastoma protein (pRb) pathway participates in cardiomyocyte hypertrophy. MicroRNAs (miRNAs), the endogenous small non-coding RNAs, were recognized to play significant roles in cardiac hypertrophy. But, it remains unknown whether cyclin/Rb pathway is modulated by miRNAs during cardiac...

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Detalles Bibliográficos
Autores principales: Huang, Shuai, Zou, Xiao, Zhu, Jie-Ning, Fu, Yong-Heng, Lin, Qiu-Xiong, Liang, Ye-You, Deng, Chun-Yu, Kuang, Su-Juan, Zhang, Meng-Zhen, Liao, Yu-Lin, Zheng, Xi-Long, Yu, Xi-Yong, Shan, Zhi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369817/
https://www.ncbi.nlm.nih.gov/pubmed/25583328
http://dx.doi.org/10.1111/jcmm.12445

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