Cargando…

Dehydrozingerone exerts beneficial metabolic effects in high-fat diet-induced obese mice viaAMPK activation in skeletal muscle

Dehydrozingerone (DHZ) exerts beneficial effects on human health; however, its mechanism of action remains unclear. Here, we found that DHZ suppressed high-fat diet-induced weight gain, lipid accumulation and hyperglycaemia in C57BL/6 mice and increased AMP-activated protein kinase (AMPK) phosphoryl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Su Jin, Kim, Hong Min, Lee, Eun Soo, Kim, Nami, Lee, Jung Ok, Lee, Hye Jeong, Park, Na Yeon, Jo, Joo Yeon, Ham, Bo Young, Han, Si Hyun, Park, Sun Hwa, Chung, Choon Hee, Kim, Hyeon Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369818/ https://www.ncbi.nlm.nih.gov/pubmed/25582026 http://dx.doi.org/10.1111/jcmm.12455

Ejemplares similares

Dehydrozingerone inhibits renal lipotoxicity in high‐fat diet–induced obese mice
por: Lee, Eun Soo, et al.
Publicado: (2021)

Dibenzoylmethane Exerts Metabolic Activity through Regulation of AMP-Activated Protein Kinase (AMPK)-Mediated Glucose Uptake and Adipogenesis Pathways
por: Kim, Nami, et al.
Publicado: (2015)

Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation
por: Lee, Jung Ok, et al.
Publicado: (2016)

AMPK, a metabolic sensor, is involved in isoeugenol-induced glucose uptake in muscle cells
por: Kim, Nami, et al.
Publicado: (2016)

Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells
por: Kim, Nami, et al.
Publicado: (2017)

The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2
por: Lee, Jung Ok, et al.
Publicado: (2020)

Dehydrozingerone promotes healing of diabetic foot ulcers: a molecular insight
por: Begum, Farmiza, et al.
Publicado: (2022)

The Stimulatory Effect of Essential Fatty Acids on Glucose Uptake Involves Both Akt and AMPK Activation in C2C12 Skeletal Muscle Cells
por: Park, So Yeon, et al.
Publicado: (2014)

Beneficial Effect of Taraxacum coreanum Nakai via the Activation of LKB1-AMPK Signaling Pathway on Obesity
por: Shin, Mi-Rae, et al.
Publicado: (2021)

Alcohol induces cell proliferation via hypermethylation of ADHFE1 in colorectal cancer cells
por: Moon, Ji Wook, et al.
Publicado: (2014)

Identification of novel hypermethylated genes and demethylating effect of vincristine in colorectal cancer
por: Moon, Ji Wook, et al.
Publicado: (2014)

Soft tissue pseudotumors of the hand and wrist mimicking malignancy: Two case reports
por: Kim, Jong Ok, et al.
Publicado: (2023)

Eicosapentaenoic Acid (EPA) Modulates Glucose Metabolism by Targeting AMP-Activated Protein Kinase (AMPK) Pathway
por: Kim, Nami, et al.
Publicado: (2019)

Anti-diabetic effect of black ginseng extract by augmentation of AMPK protein activity and upregulation of GLUT2 and GLUT4 expression in db/db mice
por: Kang, Ok-Hwa, et al.
Publicado: (2017)

Efficacy and Safety of Cold-Induced Noninvasive Targeted Fat Reduction in Pseudogynecomastia
por: Hong, Ji Yeon, et al.
Publicado: (2022)

Lactiplantibacillusplantarum ATG-K2 Exerts an Anti-Obesity Effect in High-Fat Diet-Induced Obese Mice by Modulating the Gut Microbiome
por: Lee, Young-Sil, et al.
Publicado: (2021)

Retro-Curcuminoids as Mimics of Dehydrozingerone and Curcumin: Synthesis, NMR, X-ray, and Cytotoxic Activity
por: Obregón-Mendoza, Marco A., et al.
Publicado: (2016)

Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling
por: Lee, Geum-Hwa, et al.
Publicado: (2020)

Rice Bran Extract Suppresses High-Fat Diet-Induced Hyperlipidemia and Hepatosteatosis through Targeting AMPK and STAT3 Signaling
por: Son, Joe Eun, et al.
Publicado: (2023)

Angiotensin II affects inflammation mechanisms via AMPK-related signalling pathways in HL-1 atrial myocytes
por: Kim, Nami, et al.
Publicado: (2017)

Effects of Yogurt Containing Fermented Pepper Juice on the Body Fat and Cholesterol Level in High Fat and High Cholesterol Diet Fed Rat
por: Yeon, Su-Jung, et al.
Publicado: (2015)

Vav3, a GEF for RhoA, Plays a Critical Role under High Glucose Conditions
por: Sha, Jie, et al.
Publicado: (2014)

Differential Methylation Pattern of ID4, SFRP1, and SHP1 between Acute Myeloid Leukemia and Chronic Myeloid Leukemia
por: Uhm, Kyung-Ok, et al.
Publicado: (2009)

Rotator cuff muscle stem cells: the double-edged sword in the skeletal muscle
por: Lee, Yong-Soo, et al.
Publicado: (2020)

Noncanonical functions of glucocorticoids: A novel role for glucocorticoids in performing multiple beneficial functions in endometrial stem cells
por: Park, Se-Ra, et al.
Publicado: (2021)

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo
por: Mapoung, Sariya, et al.
Publicado: (2020)

Is fasting beneficial for hospitalized patients with inflammatory bowel diseases?
por: Park, Yong Eun, et al.
Publicado: (2020)

Beneficial Effects of Deoxyshikonin on Delayed Wound Healing in Diabetic Mice
por: Park, Jun Yeon, et al.
Publicado: (2018)

Android Fat Depot Is More Closely Associated with Metabolic Syndrome than Abdominal Visceral Fat in Elderly People
por: Kang, Seon Mee, et al.
Publicado: (2011)

Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways
por: Park, Jun Sung, et al.
Publicado: (2023)

Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1–AMPK–mTOR axis
por: Jung, Taek-Yeol, et al.
Publicado: (2020)

Nicotinamide Exerts Antioxidative Effects on Senescent Cells
por: Kwak, Ju Yeon, et al.
Publicado: (2015)

Allium macrostemon whole extract ameliorates obesity-induced inflammation and endoplasmic reticulum stress in adipose tissue of high-fat diet-fed C57BL/6N mice
por: Kim, Juhae, et al.
Publicado: (2023)

The age-dependent induction of apoptosis-inducing factor (AIF) in the human semitendinosus skeletal muscle
por: Park, Soo Yeon, et al.
Publicado: (2009)

Inhibition of MUC1 exerts cell-cycle arrest and telomerase suppression in glioblastoma cells
por: Kim, Sojin, et al.
Publicado: (2020)

Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways
por: Jeong, Heeyoon, et al.
Publicado: (2017)

Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)
por: Lee, Myoung-Sun, et al.
Publicado: (2016)

Antidepressant-like effect of dehydrozingerone from Zingiber officinale by elevating monoamines in brain: in silico and in vivo studies
por: Moorkoth, Sudheer, et al.
Publicado: (2021)

Dehydrozingerone Alleviates Hyperalgesia, Oxidative Stress and Inflammatory Factors in Complete Freund’s Adjuvant-Induced Arthritic Rats
por: Liu, Chunhong, et al.
Publicado: (2022)

Sargassum thunbergii Extract Attenuates High-Fat Diet-Induced Obesity in Mice by Modulating AMPK Activation and the Gut Microbiota
por: Kim, Dahee, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4vofl8a5jgin3l9bbhvvpc30ds