A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid

INTRODUCTION: Amyloid β-protein oligomers play a key role in Alzheimer’s disease (AD), but well-validated assays that routinely detect them in cerebrospinal fluid (CSF) are just emerging. We sought to confirm and extend a recent study using the Singulex Erenna platform that reported increased mean C...

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Detalles Bibliográficos
Autores principales: Yang, Ting, O’Malley, Tiernan T, Kanmert, Daniel, Jerecic, Jasna, Zieske, Lynn R, Zetterberg, Henrik, Hyman, Bradley T, Walsh, Dominic M, Selkoe, Dennis J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369838/
https://www.ncbi.nlm.nih.gov/pubmed/25802556
http://dx.doi.org/10.1186/s13195-015-0100-y

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