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Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

INTRODUCTION: Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity c...

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Detalles Bibliográficos
Autores principales: Ulusoy, Ayse, Musgrove, Ruth E, Rusconi, Raffaella, Klinkenberg, Michael, Helwig, Michael, Schneider, Anja, Di Monte, Donato A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369863/
https://www.ncbi.nlm.nih.gov/pubmed/25853980
http://dx.doi.org/10.1186/s40478-015-0198-y