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Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine

Indoxyl sulfate (IS) contributes to oxidative stress and endothelial dysfunction in chronic kidney disease patients. However, the role of mitochondria in IS-induced oxidative stress is not very clear. In this study, we examined whether mitochondria play a pivotal role in modulating the effects of an...

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Detalles Bibliográficos
Autores principales:	Lee, Wen-Chin, Li, Lung-Chih, Chen, Jin-Bor, Chang, Hsueh-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369955/ https://www.ncbi.nlm.nih.gov/pubmed/25839054 http://dx.doi.org/10.1155/2015/620826

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