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Primary hepatic tuberculosis presenting as acute liver failure

Abdominal tuberculosis is a common clinical entity in Indian subcontinent; however, hepatic tuberculosis in the absence of miliary abdominal tuberculosis is restricted to the case reports and small case series in English literature. It mimics common liver diseases like liver abscess and tumors. We r...

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Autores principales: Jain, Deepak, Aggarwal, H. K., Jain, Promil, Pawar, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370019/
https://www.ncbi.nlm.nih.gov/pubmed/25988063
http://dx.doi.org/10.1093/omcr/omu058
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author Jain, Deepak
Aggarwal, H. K.
Jain, Promil
Pawar, Sunil
author_facet Jain, Deepak
Aggarwal, H. K.
Jain, Promil
Pawar, Sunil
author_sort Jain, Deepak
collection PubMed
description Abdominal tuberculosis is a common clinical entity in Indian subcontinent; however, hepatic tuberculosis in the absence of miliary abdominal tuberculosis is restricted to the case reports and small case series in English literature. It mimics common liver diseases like liver abscess and tumors. We report a case of 25-year-old immunocompetent female who presented with features of acute liver failure. Ultrasonography (USG) abdomen revealed multiple hypoechoic lesions. However, patient expired within 48 h of presentation but her liver autopsy revealed multiple epithelioid cell caseating granulomas with positive staining for acid fast bacilli (AFB). Polymerase chain reaction (PCR) was also positive for Mycobacterium tuberculosis.
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spelling pubmed-43700192015-05-18 Primary hepatic tuberculosis presenting as acute liver failure Jain, Deepak Aggarwal, H. K. Jain, Promil Pawar, Sunil Oxf Med Case Reports Case Reports Abdominal tuberculosis is a common clinical entity in Indian subcontinent; however, hepatic tuberculosis in the absence of miliary abdominal tuberculosis is restricted to the case reports and small case series in English literature. It mimics common liver diseases like liver abscess and tumors. We report a case of 25-year-old immunocompetent female who presented with features of acute liver failure. Ultrasonography (USG) abdomen revealed multiple hypoechoic lesions. However, patient expired within 48 h of presentation but her liver autopsy revealed multiple epithelioid cell caseating granulomas with positive staining for acid fast bacilli (AFB). Polymerase chain reaction (PCR) was also positive for Mycobacterium tuberculosis. Oxford University Press 2014-12-23 /pmc/articles/PMC4370019/ /pubmed/25988063 http://dx.doi.org/10.1093/omcr/omu058 Text en © The Author 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Jain, Deepak
Aggarwal, H. K.
Jain, Promil
Pawar, Sunil
Primary hepatic tuberculosis presenting as acute liver failure
title Primary hepatic tuberculosis presenting as acute liver failure
title_full Primary hepatic tuberculosis presenting as acute liver failure
title_fullStr Primary hepatic tuberculosis presenting as acute liver failure
title_full_unstemmed Primary hepatic tuberculosis presenting as acute liver failure
title_short Primary hepatic tuberculosis presenting as acute liver failure
title_sort primary hepatic tuberculosis presenting as acute liver failure
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370019/
https://www.ncbi.nlm.nih.gov/pubmed/25988063
http://dx.doi.org/10.1093/omcr/omu058
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