Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea

One-third to half of patients taking clozapine suffer from refractory symptoms despite adequate treatment. Among other adverse effects, clozapine-induced hypersalivation (CIH) occurs in approximately half of all patients. This is a case of a 30-year-old male with refractory schizophrenia; in this pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Bogorni, Fabiani, Moreira, Frederico Fernandes, Pimentel, Eduardo Mylius, Grohs, Géder Evandro Motta, Diaz, Alexandre Paim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370110/
https://www.ncbi.nlm.nih.gov/pubmed/25838958
http://dx.doi.org/10.1155/2015/408179
_version_ 1782362842326892544
author Bogorni, Fabiani
Moreira, Frederico Fernandes
Pimentel, Eduardo Mylius
Grohs, Géder Evandro Motta
Diaz, Alexandre Paim
author_facet Bogorni, Fabiani
Moreira, Frederico Fernandes
Pimentel, Eduardo Mylius
Grohs, Géder Evandro Motta
Diaz, Alexandre Paim
author_sort Bogorni, Fabiani
collection PubMed
description One-third to half of patients taking clozapine suffer from refractory symptoms despite adequate treatment. Among other adverse effects, clozapine-induced hypersalivation (CIH) occurs in approximately half of all patients. This is a case of a 30-year-old male with refractory schizophrenia; in this patient, the remission of residual positive symptoms, as well as the reduction of CIH, was achieved by treatment with clozapine augmented with amisulpride.
format Online
Article
Text
id pubmed-4370110
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43701102015-04-02 Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea Bogorni, Fabiani Moreira, Frederico Fernandes Pimentel, Eduardo Mylius Grohs, Géder Evandro Motta Diaz, Alexandre Paim Case Rep Psychiatry Case Report One-third to half of patients taking clozapine suffer from refractory symptoms despite adequate treatment. Among other adverse effects, clozapine-induced hypersalivation (CIH) occurs in approximately half of all patients. This is a case of a 30-year-old male with refractory schizophrenia; in this patient, the remission of residual positive symptoms, as well as the reduction of CIH, was achieved by treatment with clozapine augmented with amisulpride. Hindawi Publishing Corporation 2015 2015-03-09 /pmc/articles/PMC4370110/ /pubmed/25838958 http://dx.doi.org/10.1155/2015/408179 Text en Copyright © 2015 Fabiani Bogorni et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bogorni, Fabiani
Moreira, Frederico Fernandes
Pimentel, Eduardo Mylius
Grohs, Géder Evandro Motta
Diaz, Alexandre Paim
Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title_full Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title_fullStr Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title_full_unstemmed Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title_short Amisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
title_sort amisulpride augmentation for clozapine-refractory positive symptoms: additional benefit in reducing hypersialorrhea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370110/
https://www.ncbi.nlm.nih.gov/pubmed/25838958
http://dx.doi.org/10.1155/2015/408179
work_keys_str_mv AT bogornifabiani amisulprideaugmentationforclozapinerefractorypositivesymptomsadditionalbenefitinreducinghypersialorrhea
AT moreirafredericofernandes amisulprideaugmentationforclozapinerefractorypositivesymptomsadditionalbenefitinreducinghypersialorrhea
AT pimenteleduardomylius amisulprideaugmentationforclozapinerefractorypositivesymptomsadditionalbenefitinreducinghypersialorrhea
AT grohsgederevandromotta amisulprideaugmentationforclozapinerefractorypositivesymptomsadditionalbenefitinreducinghypersialorrhea
AT diazalexandrepaim amisulprideaugmentationforclozapinerefractorypositivesymptomsadditionalbenefitinreducinghypersialorrhea

Ejemplares similares