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Optimization of the convection volume in online post-dilution haemodiafiltration: practical and technical issues

In post-dilution online haemodiafiltration (ol-HDF), a relationship has been demonstrated between the magnitude of the convection volume and survival. However, to achieve high convection volumes (>22 L per session) detailed notion of its determining factors is highly desirable. This manuscript su...

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Detalles Bibliográficos
Autores principales: Chapdelaine, Isabelle, de Roij van Zuijdewijn, Camiel L.M., Mostovaya, Ira M., Lévesque, Renée, Davenport, Andrew, Blankestijn, Peter J., Wanner, Christoph, Nubé, Menso J., Grooteman, Muriel P.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370303/
https://www.ncbi.nlm.nih.gov/pubmed/25815176
http://dx.doi.org/10.1093/ckj/sfv003
Descripción
Sumario:In post-dilution online haemodiafiltration (ol-HDF), a relationship has been demonstrated between the magnitude of the convection volume and survival. However, to achieve high convection volumes (>22 L per session) detailed notion of its determining factors is highly desirable. This manuscript summarizes practical problems and pitfalls that were encountered during the quest for high convection volumes. Specifically, it addresses issues such as type of vascular access, needles, blood flow rate, recirculation, filtration fraction, anticoagulation and dialysers. Finally, five of the main HDF systems in Europe are briefly described as far as HDF prescription and optimization of the convection volume is concerned.