Cargando…

Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene

BACKGROUND: Patients with autism spectrum disorder (ASD) may have low brain serotonin concentrations as reflected by the serotonin end-metabolite 5-hydroxyindolacetic acid (5HIAA) in cerebrospinal fluid (CSF). METHODS: We sequenced the candidate genes SLC6A4 (SERT), SLC29A4 (PMAT), and GCHFR (GFRP),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adamsen, Dea, Ramaekers, Vincent, Ho, Horace TB, Britschgi, Corinne, Rüfenacht, Véronique, Meili, David, Bobrowski, Elise, Philippe, Paule, Nava, Caroline, Van Maldergem, Lionel, Bruggmann, Rémy, Walitza, Susanne, Wang, Joanne, Grünblatt, Edna, Thöny, Beat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370364/ https://www.ncbi.nlm.nih.gov/pubmed/25802735 http://dx.doi.org/10.1186/2040-2392-5-43

Ejemplares similares

Uncovering Functional Contributions of PMAT (Slc29a4) to Monoamine Clearance Using Pharmacobehavioral Tools
por: Beaver, Jasmin N., et al.
Publicado: (2022)

Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism
por: Nyffeler, Johanna, et al.
Publicado: (2014)

The acyltransferase PMAT1 malonylates brassinolide glucoside
por: Gan, Sufu, et al.
Publicado: (2021)

Heterotypic Stressors Unmask Behavioral Influences of PMAT Deficiency in Mice
por: Weber, Brady L., et al.
Publicado: (2023)

Heterotypic stressors unmask behavioral influences of PMAT deficiency in mice
por: Weber, Brady L, et al.
Publicado: (2023)

Methylphenidate enhances neuronal differentiation and reduces proliferation concomitant to activation of Wnt signal transduction pathways
por: Grünblatt, Edna, et al.
Publicado: (2018)

Structure-Function Relationships in PMA and PMAT Series Copolymers for Polymer Solar Cells
por: Chen, Jhe-Han, et al.
Publicado: (2018)

Oxidative Stress, Folate Receptor Autoimmunity, and CSF Findings in Severe Infantile Autism
por: Ramaekers, Vincent T., et al.
Publicado: (2020)

The neurobiological link between OCD and ADHD
por: Brem, Silvia, et al.
Publicado: (2014)

Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View
por: Jagannath, Vinita, et al.
Publicado: (2017)

A pilot investigation on DNA methylation modifications associated with complex posttraumatic symptoms in elderly traumatized in childhood
por: Marinova, Zoya, et al.
Publicado: (2017)

Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain
por: Jagannath, Vinita, et al.
Publicado: (2017)

Association study and a systematic meta-analysis of the VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder
por: Grünblatt, Edna, et al.
Publicado: (2019)

Media use and emotional distress under COVID-19 lockdown in a clinical sample referred for internalizing disorders: A Swiss adolescents' perspective
por: Werling, Anna Maria, et al.
Publicado: (2022)

ADHD: Current Concepts and Treatments in Children and Adolescents
por: Drechsler, Renate, et al.
Publicado: (2020)

A novel missense variant in SLC18A2 causes recessive brain monoamine vesicular transport disease and absent serotonin in platelets
por: Padmakumar, Manisha, et al.
Publicado: (2019)

Profiling parvalbumin interneurons using iPSC: challenges and perspectives for Autism Spectrum Disorder (ASD)
por: Filice, Federica, et al.
Publicado: (2020)

Improved Generation of Induced Pluripotent Stem Cells From Hair Derived Keratinocytes – A Tool to Study Neurodevelopmental Disorders as ADHD
por: Re, Silvano, et al.
Publicado: (2018)

Growth rates of human induced pluripotent stem cells and neural stem cells from attention-deficit hyperactivity disorder patients: a preliminary study
por: Yde Ohki, Cristine Marie, et al.
Publicado: (2023)

Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteers
por: Jönsson, Erik G, et al.
Publicado: (2004)

Evidence for PMAT- and OCT-like biogenic amine transporters in a probiotic strain of Lactobacillus: Implications for interkingdom communication within the microbiota-gut-brain axis
por: Lyte, Mark, et al.
Publicado: (2018)

Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction
por: Grünblatt, Edna, et al.
Publicado: (2015)

DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma
por: Marinova, Zoya, et al.
Publicado: (2017)

High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder
por: Grünblatt, Edna, et al.
Publicado: (2017)

Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis: The Relationship of DAO, DAOA, and NRG1 Variants with Negative Symptoms and Cognitive Deficits
por: Jagannath, Vinita, et al.
Publicado: (2017)

The stress–Wnt-signaling axis: a hypothesis for attention-deficit hyperactivity disorder and therapy approaches
por: Yde Ohki, Cristine Marie, et al.
Publicado: (2020)

Minireview on Glutamine Synthetase Deficiency, an Ultra-Rare Inborn Error of Amino Acid Biosynthesis
por: Spodenkiewicz, Marta, et al.
Publicado: (2016)

Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man
por: Rivera-Barahona, Ana, et al.
Publicado: (2015)

Correction: Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man
por: Rivera-Barahona, Ana, et al.
Publicado: (2015)

No Association of Variants of the NPY-System With Obsessive-Compulsive Disorder in Children and Adolescents
por: Franke, Maximilian, et al.
Publicado: (2019)

Protocol for a Wnt reporter assay to measure its activity in human neural stem cells derived from induced pluripotent stem cells
por: Yde Ohki, Cristine Marie, et al.
Publicado: (2023)

The Utility of CSF for the Diagnosis of Primary and Secondary Monoamine Neurotransmitter Deficiencies
por: Burlina, A.B., et al.
Publicado: (2017)

From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis
por: Grünblatt, Edna, et al.
Publicado: (2023)

Effects of Monoamines and Antidepressants on Astrocyte Physiology: Implications for Monoamine Hypothesis of Depression
por: Marathe, Swananda V, et al.
Publicado: (2018)

Editorial: Obsessive-compulsive related disorders (OCRD) across the lifespan
por: Lochner, Christine, et al.
Publicado: (2023)

Depression as a Neuroendocrine Disorder: Emerging Neuropsychopharmacological Approaches beyond Monoamines
por: Chávez-Castillo, Mervin, et al.
Publicado: (2019)

The discrediting of the monoamine hypothesis
por: Hinz, Marty, et al.
Publicado: (2012)

Expression of organic cation transporter 3 (SLC22A3) and plasma membrane monoamine transporter (SLC29A4) in human umbilical vein endothelial cells and their relevance for histamine uptake
por: Ferk, Polonca, et al.
Publicado: (2012)

Monoamine Oxidase-A Occupancy by Moclobemide and Phenelzine: Implications for the Development of Monoamine Oxidase Inhibitors
por: Chiuccariello, Lina, et al.
Publicado: (2015)

Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorders: Diagnosis, Treatment and Prevention
por: Bobrowski-Khoury, Natasha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n4tpjdohfonar00scnfhhmveag