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P2Y12 expression and function in alternatively activated human microglia

OBJECTIVE: To investigate and measure the functional significance of altered P2Y12 expression in the context of human microglia activation. METHODS: We performed in vitro and in situ experiments to measure how P2Y12 expression can influence disease-relevant functional properties of classically activ...

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Detalles Bibliográficos
Autores principales: Moore, Craig S., Ase, Ariel R., Kinsara, Angham, Rao, Vijayaraghava T.S., Michell-Robinson, Mackenzie, Leong, Soo Yuen, Butovsky, Oleg, Ludwin, Samuel K., Séguéla, Philippe, Bar-Or, Amit, Antel, Jack P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370387/
https://www.ncbi.nlm.nih.gov/pubmed/25821842
http://dx.doi.org/10.1212/NXI.0000000000000080