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Non-Viral Nanoparticle Delivers Small Interfering RNA to Macrophages In Vitro and In Vivo

Macrophages are increasingly being viewed as therapeutic target for various cancers and many inflammatory diseases. Sequence specific gene reduction by siRNA represents an attractive approach to modulate macrophage function. However, delivery of the therapeutic siRNA into macrophages by non-viral na...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Gao, Yunxiang, Caja, Kevin, Zhao, Bocheng, Kim, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370462/
https://www.ncbi.nlm.nih.gov/pubmed/25799489
http://dx.doi.org/10.1371/journal.pone.0118472