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Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance

SIRT1 is a NAD(+)-dependent deacetylase thought to regulate cellular metabolic pathways in response to alterations in nutrient flux. In the current study we investigated whether acute changes in SIRT1 expression affect markers of muscle mitochondrial content and also determined whether SIRT1 influen...

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Detalles Bibliográficos
Autores principales:	Brandon, Amanda E., Tid-Ang, Jennifer, Wright, Lauren E., Stuart, Ella, Suryana, Eurwin, Bentley, Nicholas, Turner, Nigel, Cooney, Gregory J., Ruderman, Neil B., Kraegen, Edward W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370576/ https://www.ncbi.nlm.nih.gov/pubmed/25798922 http://dx.doi.org/10.1371/journal.pone.0121959

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