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NLRP3 Inflammasome Activation in Dialyzed Chronic Kidney Disease Patients

To assess whether NLR pyrin domain-containing protein 3 (NLRP3) inflammasome, a multiprotein complex that mediates the activation of caspase-1 (CASP-1) and pro-inflammatory cytokines IL-18 and IL-1β, could be involved in the chronic inflammatory state observed in chronic kidney disease patients unde...

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Detalles Bibliográficos
Autores principales:	Granata, Simona, Masola, Valentina, Zoratti, Elisa, Scupoli, Maria Teresa, Baruzzi, Anna, Messa, Michele, Sallustio, Fabio, Gesualdo, Loreto, Lupo, Antonio, Zaza, Gianluigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370586/ https://www.ncbi.nlm.nih.gov/pubmed/25798846 http://dx.doi.org/10.1371/journal.pone.0122272

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