Cargando…

Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways

Transient receptor potential melastatin 7 (TRPM7), a non-selective cation channel, is highly expressed expressed in the brain and plays a critical role in ischemic neuronal death. Astrocyte, the most abundant cell type in central nervous system (CNS), exerts many essential functions in the physiolog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Zhao, Leng, Tiandong, Feng, Xuechao, Sun, Huawei, Inoue, Koichi, Zhu, Li, Xiong, Zhi-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370640/ https://www.ncbi.nlm.nih.gov/pubmed/25799367 http://dx.doi.org/10.1371/journal.pone.0119912

Ejemplares similares

Role of TRPM7 Channels in Hyperglycemia-Mediated Injury of Vascular Endothelial Cells
por: Sun, Huawei, et al.
Publicado: (2013)

TRPM8 Inhibition Regulates the Proliferation, Migration and ROS Metabolism of Bladder Cancer Cells
por: Wang, Gang, et al.
Publicado: (2020)

ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway
por: Liu, Mingli, et al.
Publicado: (2016)

A Low-Level Carbon Dioxide Laser Promotes Fibroblast Proliferation and Migration through Activation of Akt, ERK, and JNK
por: Shingyochi, Yoshiaki, et al.
Publicado: (2017)

JNK Signaling Regulates Cellular Mechanics of Cortical Interneuron Migration
por: Smith, Skye E., et al.
Publicado: (2020)

Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer
por: Lee, Eun Hye, et al.
Publicado: (2020)

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
por: Chen, Wen-Liang, et al.
Publicado: (2015)

Acid Sensing Ion Channels (ASICs) in NS20Y cells – potential role in neuronal differentiation
por: O’Bryant, Zaven, et al.
Publicado: (2016)

LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway
por: Xing, Ying, et al.
Publicado: (2021)

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways
por: Hsieh, Hsi-Lung, et al.
Publicado: (2010)

Fisetin regulates astrocyte migration and proliferation in vitro
por: Wang, Nan, et al.
Publicado: (2017)

TRPM7 is overexpressed in bladder cancer and promotes proliferation, migration, invasion and tumor growth
por: Gao, Sheng-Lin, et al.
Publicado: (2017)

Treatment for ischemic stroke: From thrombolysis to thrombectomy and remaining challenges
por: Leng, Tiandong, et al.
Publicado: (2019)

Neuropilin1 silencing impairs the proliferation and migration of cells in pancreatic cancer
por: He, Li‐Hong, et al.
Publicado: (2020)

Xyloketal B Suppresses Glioblastoma Cell Proliferation and Migration in Vitro through Inhibiting TRPM7-Regulated PI3K/Akt and MEK/ERK Signaling Pathways
por: Chen, Wen-Liang, et al.
Publicado: (2015)

Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/ p38 MAPK signaling pathway
por: Yang, Jian, et al.
Publicado: (2017)

The ERK and JNK pathways in the regulation of metabolic reprogramming
por: Papa, Salvatore, et al.
Publicado: (2018)

Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways
por: Nagayama, Kosuke, et al.
Publicado: (2015)

Icariside II Enhances Nrf2 Nuclear Translocation to Upregulate Phase II Detoxifying Enzyme Expression Coupled with the ERK, Akt and JNK Signaling Pathways
por: Gu, Jing, et al.
Publicado: (2011)

TRPM7 regulates proliferation and polarisation of macrophages
por: Schilling, Tom, et al.
Publicado: (2014)

Low-intensity pulsed ultrasound promotes proliferation and migration of HaCaT keratinocytes through the PI3K/AKT and JNK pathways
por: Leng, Xiaoyan, et al.
Publicado: (2018)

Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways
por: Che, Xianping, et al.
Publicado: (2021)

The inhibitory effect of silencing CDCA3 on migration and proliferation in bladder urothelial carcinoma
por: Shen, Dexin, et al.
Publicado: (2021)

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation
por: Lv, Jian-Min, et al.
Publicado: (2018)

Vanillin oxime inhibits lung cancer cell proliferation and activates apoptosis through JNK/ERK-CHOP pathway
por: Shen, Jie, et al.
Publicado: (2021)

Silencing of Transcription Factor Sp1 Promotes SN1 Transporter Regulation by Ammonia in Mouse Cortical Astrocytes
por: Dąbrowska, Katarzyna, et al.
Publicado: (2019)

N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation
por: Zhang, Zheng, et al.
Publicado: (2014)

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7‐mediated chondroitin sulfate proteoglycan production
por: Kamermans, Alwin, et al.
Publicado: (2018)

BMAL1 promotes colorectal cancer cell migration and invasion through ERK‐ and JNK‐dependent c‐Myc expression
por: Shan, Lina, et al.
Publicado: (2022)

ERK and JNK Activation is Essential for Oncogenic Transformation by v-Rel
por: Kralova, Jarmila, et al.
Publicado: (2010)

JNK, p38, ERK, and SGK1 Inhibitors in Cancer
por: Cicenas, Jonas, et al.
Publicado: (2017)

Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer
por: Martínez-Martínez, Desirée, et al.
Publicado: (2021)

Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis
por: Srinivasan, Ruchika, et al.
Publicado: (2009)

Silencing PRSS1 suppresses the growth and proliferation of gastric carcinoma cells via the ERK pathway
por: Ye, Dongmei, et al.
Publicado: (2021)

SAK-HV Decreases the Self-Ubiquitination of MEKK1 to Promote Macrophage Proliferation via MAPK/ERK and JNK Pathways
por: Zhang, Chao, et al.
Publicado: (2017)

Astrocytic modulation of cortical oscillations
por: Bellot-Saez, Alba, et al.
Publicado: (2018)

Methylation-mediated silencing of EDN3 promotes cervical cancer proliferation, migration and invasion
por: Zhu, Peng, et al.
Publicado: (2023)

RASSF9 promotes NSCLC cell proliferation by activating the MEK/ERK axis
por: Yuan, Jun, et al.
Publicado: (2021)

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
por: Cao, Rui, et al.
Publicado: (2016)

Sonic Hedgehog Regulates Proliferation, Migration and Invasion of Synoviocytes in Rheumatoid Arthritis via JNK Signaling
por: Zhu, Shangling, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nd40m04bj042iievq4v8m58ad4