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Abrogation of Plasminogen Activator Inhibitor-1-Vitronectin Interaction Ameliorates Acute Kidney Injury in Murine Endotoxemia

Sepsis-induced acute kidney injury (AKI) contributes to the high mortality and morbidity in patients. Although the pathogenesis of AKI during sepsis is poorly understood, it is well accepted that plasminogen activator inhibitor-1 (PAI-1) and vitronectin (Vn) are involved in AKI. However, the functio...

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Detalles Bibliográficos
Autores principales:	Gupta, Kamlesh K., Donahue, Deborah L., Sandoval-Cooper, Mayra J., Castellino, Francis J., Ploplis, Victoria A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370643/ https://www.ncbi.nlm.nih.gov/pubmed/25799354 http://dx.doi.org/10.1371/journal.pone.0120728

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