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Alternative Polyadenylation Allows Differential Negative Feedback of Human miRNA miR-579 on Its Host Gene ZFR

About half of the known miRNA genes are located within protein-coding host genes, and are thus subject to co-transcription. Accumulating data indicate that this coupling may be an intrinsic mechanism to directly regulate the host gene’s expression, constituting a negative feedback loop. Inevitably,...

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Detalles Bibliográficos
Autores principales: Hinske, Ludwig Christian, Galante, Pedro A. F., Limbeck, Elisabeth, Möhnle, Patrick, Parmigiani, Raphael B., Ohno-Machado, Lucila, Camargo, Anamaria A., Kreth, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370670/
https://www.ncbi.nlm.nih.gov/pubmed/25799583
http://dx.doi.org/10.1371/journal.pone.0121507