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Modulation of NF-κB/miR-21/PTEN Pathway Sensitizes Non-Small Cell Lung Cancer to Cisplatin

BACKGROUND: Platinum-based chemotherapy is a standard strategy for non-small cell lung cancer (NSCLC), while chemoresistance remains a major therapeutic challenge in current clinical practice. Our present study was aimed to determine whether inhibition of the NF-κB/miR-21/PTEN pathway could increase...

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Detalles Bibliográficos
Autores principales: Yang, Zhenhua, Fang, Surong, Di, Yicheng, Ying, Weiwei, Tan, Yan, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370674/
https://www.ncbi.nlm.nih.gov/pubmed/25799148
http://dx.doi.org/10.1371/journal.pone.0121547