Cargando…

Modulation of NF-κB/miR-21/PTEN Pathway Sensitizes Non-Small Cell Lung Cancer to Cisplatin

BACKGROUND: Platinum-based chemotherapy is a standard strategy for non-small cell lung cancer (NSCLC), while chemoresistance remains a major therapeutic challenge in current clinical practice. Our present study was aimed to determine whether inhibition of the NF-κB/miR-21/PTEN pathway could increase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Zhenhua, Fang, Surong, Di, Yicheng, Ying, Weiwei, Tan, Yan, Gu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370674/ https://www.ncbi.nlm.nih.gov/pubmed/25799148 http://dx.doi.org/10.1371/journal.pone.0121547

Ejemplares similares

LncRNA MEG3 promotes cisplatin sensitivity of cervical cancer cells by regulating the miR-21/PTEN axis
por: Du, Ying, et al.
Publicado: (2022)

TP53TG1 enhances cisplatin sensitivity of non-small cell lung cancer cells through regulating miR-18a/PTEN axis
por: Xiao, Huijuan, et al.
Publicado: (2018)

MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN
por: Xue, Xinying, et al.
Publicado: (2016)

miR-21 regulates osteogenic and adipogenic differentiation of BMSCs by targeting PTEN
por: Zhou, Yongtao, et al.
Publicado: (2021)

miR-383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24-mediated NF-κB signaling pathway
por: He, Bo, et al.
Publicado: (2021)

miR-18a increases insulin sensitivity by inhibiting PTEN
por: Zhou, Yongqiang, et al.
Publicado: (2020)

Acupuncture Decreases NF-κB p65, miR-155, and miR-21 and Increases miR-146a Expression in Chronic Atrophic Gastritis Rats
por: Zhang, Jialing, et al.
Publicado: (2016)

NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells
por: Doukas, Sotirios G., et al.
Publicado: (2018)

MiR-21 promotes pterygium cell proliferation through the PTEN/AKT pathway
por: Li, Xia, et al.
Publicado: (2018)

Long non-coding RNA HAND2-AS1/miR-106a/PTEN axis re-sensitizes cisplatin-resistant ovarian cells to cisplatin treatment
por: Li, Lijun, et al.
Publicado: (2021)

MiR‐192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF‐κB pathway
por: Li, Yang, et al.
Publicado: (2021)

PTEN Modulates miR-21 Processing via RNA-Regulatory Protein RNH1
por: Kim, Youn-Jae, et al.
Publicado: (2011)

Effects of miR-21 on proliferation and apoptosis of WT cells via PTEN/Akt pathway
por: Zhang, Xiuli, et al.
Publicado: (2020)

Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocellular apoptosis
por: Rodrigues, Pedro M., et al.
Publicado: (2015)

Butylphthalide Inhibits TLR4/NF-κB Pathway by Upregulation of miR-21 to Have the Neuroprotective Effect
por: Zhan, Lan, et al.
Publicado: (2022)

Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer
por: Bao, Bin, et al.
Publicado: (2011)

MiR-186 bidirectionally regulates cisplatin sensitivity of ovarian cancer cells via suppressing targets PIK3R3 and PTEN and upregulating APAF1 expression
por: Xiang, Ying, et al.
Publicado: (2020)

A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model
por: Huang, Xin, et al.
Publicado: (2022)

miR-1271 enhances the sensitivity of colorectal cancer cells to cisplatin
por: Yao, Huixiang, et al.
Publicado: (2019)

miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling
por: Liu, Hongzhe, et al.
Publicado: (2014)

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
por: Peralta-Zaragoza, Oscar, et al.
Publicado: (2016)

GAS5 silencing attenuates hypoxia‐induced cardiomyocytes injury by targeting miR‐21/PTEN
por: Wang, Qianli, et al.
Publicado: (2023)

Corrigendum: Inhibition of NF-κB by deoxycholic acid induces miR-21/PDCD4-dependent hepatocellular apoptosis
por: Rodrigues, Pedro M., et al.
Publicado: (2016)

Retracted: Butylphthalide Inhibits TLR4/NF-κB Pathway by Upregulation of miR-21 to Have the Neuroprotective Effect
por: Healthcare Engineering, Journal of
Publicado: (2023)

Retraction: Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer
Publicado: (2018)

Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis
por: Qian, Rui, et al.
Publicado: (2022)

An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells
por: Wang, Caixia, et al.
Publicado: (2020)

WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis
por: Zhou, Xuan, et al.
Publicado: (2014)

Human esophageal fibroblast-derived exosomal miR-21 reduced the cisplatin sensitivity to esophageal carcinoma EC9706 cells
por: Wan, Jiajin, et al.
Publicado: (2021)

Tumor suppressor NFκB2 p100 interacts with ERK2 and stabilizes PTEN mRNA via inhibition of miR-494
por: Wang, Yulei, et al.
Publicado: (2015)

The renoprotective effect of curcumin against cisplatin-induced acute kidney injury in mice: involvement of miR-181a/PTEN axis
por: Huang, Si-Jia, et al.
Publicado: (2020)

Long non-coding RNA CASC2 enhanced cisplatin-induced viability inhibition of non-small cell lung cancer cells by regulating the PTEN/PI3K/Akt pathway through down-regulation of miR-18a and miR-21
por: Li, Li, et al.
Publicado: (2018)

MiR-1244 sensitizes the resistance of non-small cell lung cancer A549 cell to cisplatin
por: Li, Weili, et al.
Publicado: (2016)

A miR-19 regulon that controls NF-κB signaling
por: Gantier, Michael P., et al.
Publicado: (2012)

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression
por: Yang, Chengdi, et al.
Publicado: (2018)

LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis
por: Wang, Pei, et al.
Publicado: (2017)

Chandipura virus dysregulates the expression of hsa-miR-21-5p to activate NF-κB in human microglial cells
por: Pandey, Neha, et al.
Publicado: (2021)

Difluorinated-Curcumin (CDF) Restores PTEN Expression in Colon Cancer Cells by Down-Regulating miR-21
por: Roy, Sanchita, et al.
Publicado: (2013)

MiR-21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN
por: Wang, Li-Juan, et al.
Publicado: (2015)

Exosomal miR-21 regulates the TETs/PTENp1/PTEN pathway to promote hepatocellular carcinoma growth
por: Cao, Liang-qi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_74lqp7a0ovkc587jvordubo1gu