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ASM-024, a Piperazinium Compound, Promotes the In Vitro Relaxation of β2-Adrenoreceptor Desensitized Tracheas

Inhaled β2-adrenoreceptor agonists are widely used in asthma and chronic obstructive pulmonary disease (COPD) for bronchoconstriction relief. β2-adrenoreceptor agonists relax airway smooth muscle cells via cyclic adenosine monophosphate (cAMP) mediated pathways. However, prolonged stimulation induce...

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Detalles Bibliográficos
Autores principales:	Israël-Assayag, Evelyne, Beaulieu, Marie-Josée, Cormier, Yvon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370676/ https://www.ncbi.nlm.nih.gov/pubmed/25799096 http://dx.doi.org/10.1371/journal.pone.0120095

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