Genome-Wide Association Studies in Dogs and Humans Identify ADAMTS20 as a Risk Variant for Cleft Lip and Palate

Cleft lip with or without cleft palate (CL/P) is the most commonly occurring craniofacial birth defect. We provide insight into the genetic etiology of this birth defect by performing genome-wide association studies in two species: dogs and humans. In the dog, a genome-wide association study of 7 CL...

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Detalles Bibliográficos
Autores principales: Wolf, Zena T., Brand, Harrison A., Shaffer, John R., Leslie, Elizabeth J., Arzi, Boaz, Willet, Cali E., Cox, Timothy C., McHenry, Toby, Narayan, Nicole, Feingold, Eleanor, Wang, Xioajing, Sliskovic, Saundra, Karmi, Nili, Safra, Noa, Sanchez, Carla, Deleyiannis, Frederic W. B., Murray, Jeffrey C., Wade, Claire M., Marazita, Mary L., Bannasch, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370697/
https://www.ncbi.nlm.nih.gov/pubmed/25798845
http://dx.doi.org/10.1371/journal.pgen.1005059

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