Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells

The aim of this study is to investigate the molecular mechanisms underlying delayed progressive pulmonary fibrosis, a characteristic of subacute paraquat (PQ) poisoning. Epithelial-mesenchymal transition (EMT) has been proposed as a cause of organ fibrosis, and transforming growth factor-β (TGF-β) i...

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Detalles Bibliográficos
Autores principales: Yamada, Atsushi, Aki, Toshihiko, Unuma, Kana, Funakoshi, Takeshi, Uemura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370722/
https://www.ncbi.nlm.nih.gov/pubmed/25799450
http://dx.doi.org/10.1371/journal.pone.0120192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370722/
https://www.ncbi.nlm.nih.gov/pubmed/25799450
http://dx.doi.org/10.1371/journal.pone.0120192

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