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Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse
Induced pluripotent stem cells (iPSCs) have tremendous potential as a tool for disease modeling, drug testing, and other applications. Since the generation of iPSCs “captures” the genetic history of the individual cell that was reprogrammed, iPSC clones (even those derived from the same individual)...
Autores principales: | Li, Cheng, Klco, Jeffery M., Helton, Nichole M., George, Daniel R., Mudd, Jacqueline L., Miller, Christopher A., Lu, Charles, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Wilson, Richard K., Ley, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370741/ https://www.ncbi.nlm.nih.gov/pubmed/25799070 http://dx.doi.org/10.1371/journal.pone.0120585 |
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