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Susceptibility to Invasive Meningococcal Disease: Polymorphism of Complement System Genes and Neisseria meningitidis Factor H Binding Protein

BACKGROUND: Neisseria meningitidis can cause severe infection in humans. Polymorphism of Complement Factor H (CFH) is associated with altered risk of invasive meningococcal disease (IMD). We aimed to find whether polymorphism of other complement genes altered risk and whether variation of N. meningi...

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Detalles Bibliográficos
Autores principales: Bradley, Declan T., Bourke, Thomas W., Fairley, Derek J., Borrow, Raymond, Shields, Michael D., Zipfel, Peter F., Hughes, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370764/
https://www.ncbi.nlm.nih.gov/pubmed/25798599
http://dx.doi.org/10.1371/journal.pone.0120757