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Glucocorticoid receptors in the locus coeruleus mediate sleep disorders caused by repeated corticosterone treatment
Stress induced constant increase of cortisol level may lead to sleep disorder, but the mechanism remains unclear. Here we described a novel model to investigate stress mimicked sleep disorders induced by repetitive administration of corticosterone (CORT). After 7 days treatment of CORT, rats showed...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371174/ https://www.ncbi.nlm.nih.gov/pubmed/25801728 http://dx.doi.org/10.1038/srep09442 |