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Glucocorticoid receptors in the locus coeruleus mediate sleep disorders caused by repeated corticosterone treatment

Stress induced constant increase of cortisol level may lead to sleep disorder, but the mechanism remains unclear. Here we described a novel model to investigate stress mimicked sleep disorders induced by repetitive administration of corticosterone (CORT). After 7 days treatment of CORT, rats showed...

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Detalles Bibliográficos
Autores principales: Wang, Zi-Jun, Zhang, Xue-Qiong, Cui, Xiang-Yu, Cui, Su-Ying, Yu, Bin, Sheng, Zhao-Fu, Li, Sheng-Jie, Cao, Qing, Huang, Yuan-Li, Xu, Ya-Ping, Zhang, Yong-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371174/
https://www.ncbi.nlm.nih.gov/pubmed/25801728
http://dx.doi.org/10.1038/srep09442