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Characteristics of hematopoietic stem cells of umbilical cord blood

Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) betwe...

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Autores principales: Hordyjewska, Anna, Popiołek, Łukasz, Horecka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371573/
https://www.ncbi.nlm.nih.gov/pubmed/25373337
http://dx.doi.org/10.1007/s10616-014-9796-y
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author Hordyjewska, Anna
Popiołek, Łukasz
Horecka, Anna
author_facet Hordyjewska, Anna
Popiołek, Łukasz
Horecka, Anna
author_sort Hordyjewska, Anna
collection PubMed
description Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) between stem cells from umbilical cord blood, bone marrow and peripheral blood. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood, and have several advantages including high proliferation. With using proper cytokine combination, HSCs can be effectively developed into different cell lines. This process is used in medicine, especially in hematology.
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spelling pubmed-43715732015-03-27 Characteristics of hematopoietic stem cells of umbilical cord blood Hordyjewska, Anna Popiołek, Łukasz Horecka, Anna Cytotechnology Review Paper Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) between stem cells from umbilical cord blood, bone marrow and peripheral blood. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood, and have several advantages including high proliferation. With using proper cytokine combination, HSCs can be effectively developed into different cell lines. This process is used in medicine, especially in hematology. Springer Netherlands 2014-11-06 2015-05 /pmc/articles/PMC4371573/ /pubmed/25373337 http://dx.doi.org/10.1007/s10616-014-9796-y Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Review Paper
Hordyjewska, Anna
Popiołek, Łukasz
Horecka, Anna
Characteristics of hematopoietic stem cells of umbilical cord blood
title Characteristics of hematopoietic stem cells of umbilical cord blood
title_full Characteristics of hematopoietic stem cells of umbilical cord blood
title_fullStr Characteristics of hematopoietic stem cells of umbilical cord blood
title_full_unstemmed Characteristics of hematopoietic stem cells of umbilical cord blood
title_short Characteristics of hematopoietic stem cells of umbilical cord blood
title_sort characteristics of hematopoietic stem cells of umbilical cord blood
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371573/
https://www.ncbi.nlm.nih.gov/pubmed/25373337
http://dx.doi.org/10.1007/s10616-014-9796-y
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