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Characteristics of hematopoietic stem cells of umbilical cord blood
Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) betwe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371573/ https://www.ncbi.nlm.nih.gov/pubmed/25373337 http://dx.doi.org/10.1007/s10616-014-9796-y |
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author | Hordyjewska, Anna Popiołek, Łukasz Horecka, Anna |
author_facet | Hordyjewska, Anna Popiołek, Łukasz Horecka, Anna |
author_sort | Hordyjewska, Anna |
collection | PubMed |
description | Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) between stem cells from umbilical cord blood, bone marrow and peripheral blood. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood, and have several advantages including high proliferation. With using proper cytokine combination, HSCs can be effectively developed into different cell lines. This process is used in medicine, especially in hematology. |
format | Online Article Text |
id | pubmed-4371573 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-43715732015-03-27 Characteristics of hematopoietic stem cells of umbilical cord blood Hordyjewska, Anna Popiołek, Łukasz Horecka, Anna Cytotechnology Review Paper Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) between stem cells from umbilical cord blood, bone marrow and peripheral blood. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood, and have several advantages including high proliferation. With using proper cytokine combination, HSCs can be effectively developed into different cell lines. This process is used in medicine, especially in hematology. Springer Netherlands 2014-11-06 2015-05 /pmc/articles/PMC4371573/ /pubmed/25373337 http://dx.doi.org/10.1007/s10616-014-9796-y Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Review Paper Hordyjewska, Anna Popiołek, Łukasz Horecka, Anna Characteristics of hematopoietic stem cells of umbilical cord blood |
title | Characteristics of hematopoietic stem cells of umbilical cord blood |
title_full | Characteristics of hematopoietic stem cells of umbilical cord blood |
title_fullStr | Characteristics of hematopoietic stem cells of umbilical cord blood |
title_full_unstemmed | Characteristics of hematopoietic stem cells of umbilical cord blood |
title_short | Characteristics of hematopoietic stem cells of umbilical cord blood |
title_sort | characteristics of hematopoietic stem cells of umbilical cord blood |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371573/ https://www.ncbi.nlm.nih.gov/pubmed/25373337 http://dx.doi.org/10.1007/s10616-014-9796-y |
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