Cargando…

Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study

BACKGROUND: Metastasis of colorectal cancer (CRC) is directly linked to patient survival. We previously identified the novel gene Metastasis Associated in Colon Cancer 1 (MACC1) in CRC and demonstrated its importance as metastasis inducer and prognostic biomarker. Here, we investigate the geographic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koelzer, Viktor H, Herrmann, Pia, Zlobec, Inti, Karamitopoulou, Eva, Lugli, Alessandro, Stein, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371627/ https://www.ncbi.nlm.nih.gov/pubmed/25884643 http://dx.doi.org/10.1186/s12885-015-1150-z

Ejemplares similares

Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer
por: Sokol, Lena, et al.
Publicado: (2015)

Circulating MACC1 Transcripts in Colorectal Cancer Patient Plasma Predict Metastasis and Prognosis
por: Stein, Ulrike, et al.
Publicado: (2012)

MACC1-Dependent Antitumor Effect of Curcumin in Colorectal Cancer
por: Güllü, Nazli, et al.
Publicado: (2022)

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma
por: Wartenberg, Martin, et al.
Publicado: (2015)

The battle for prognosis at the invasive front of colorectal cancer
por: Lugli, Alessandro, et al.
Publicado: (2020)

DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells
por: Ivanovska, Jelena, et al.
Publicado: (2015)

Correction: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells
por: Ivanovska, Jelena, et al.
Publicado: (2017)

Tumor Budding in Upper Gastrointestinal Carcinomas
por: Koelzer, Viktor H., et al.
Publicado: (2014)

Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer
por: Koelzer, V H, et al.
Publicado: (2013)

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer
por: Galván, José A., et al.
Publicado: (2014)

Metastasis Associated in Colorectal Cancer 1 (MACC1) mRNA Expression Is Enhanced in Sporadic Vestibular Schwannoma and Correlates to Deafness
por: Breun, Maria, et al.
Publicado: (2023)

Obesity, colorectal cancer and MACC1 expression: A possible novel molecular association
por: Bähr, Ina, et al.
Publicado: (2022)

Loss of Cdx2 Expression in Primary Tumors and Lymph Node Metastases is Specific for Mismatch Repair-Deficiency in Colorectal Cancer
por: Dawson, Heather, et al.
Publicado: (2013)

Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types
por: Zlobec, Inti, et al.
Publicado: (2013)

Tumour budding: a promising parameter in colorectal cancer
por: Lugli, A, et al.
Publicado: (2012)

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer
por: Schmid, Felicitas, et al.
Publicado: (2012)

Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response
por: Hagemann, Carsten, et al.
Publicado: (2019)

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
por: Juneja, Manisha, et al.
Publicado: (2017)

Cantharidin and Its Analogue Norcantharidin Inhibit Metastasis—Inducing Genes S100A4 and MACC1
por: Schöpe, Paul Curtis, et al.
Publicado: (2023)

Role of tumor size in the pre-operative management of rectal cancer patients
por: Zlobec, Inti, et al.
Publicado: (2010)

Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)
por: Karamitopoulou, Eva, et al.
Publicado: (2013)

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients
por: Ilm, Katharina, et al.
Publicado: (2015)

Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer
por: Link, Theresa, et al.
Publicado: (2019)

CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival
por: Koelzer, Viktor H, et al.
Publicado: (2014)

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget
por: Zlobec, Inti, et al.
Publicado: (2010)

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk
por: Ashktorab, Hassan, et al.
Publicado: (2016)

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer
por: Ilm, Katharina, et al.
Publicado: (2016)

Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree?
por: Blank, Annika, et al.
Publicado: (2018)

The potential therapeutic applications and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) in cancers
por: Kopczyńska, Ewa Katarzyna
Publicado: (2016)

TIA-1 Cytotoxic Granule-Associated RNA Binding Protein Improves the Prognostic Performance of CD8 in Mismatch Repair-Proficient Colorectal Cancer
por: Zlobec, Inti, et al.
Publicado: (2010)

Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas
por: Treese, Christoph, et al.
Publicado: (2022)

Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival
por: Vuaroqueaux, Vincent, et al.
Publicado: (2022)

Evaluation of the correlation of MACC1, CD44, Twist1, and KiSS-1 in the metastasis and prognosis for colon carcinoma
por: Zhu, Bo, et al.
Publicado: (2018)

Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
por: Galván, J A, et al.
Publicado: (2015)

Clinicopathological and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) overexpression in colorectal cancer: a meta-analysis
por: Zhao, Yang, et al.
Publicado: (2016)

Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer
por: Lisec, Jan, et al.
Publicado: (2021)

Cytokeratin‐based assessment of tumour budding in colorectal cancer: analysis in stage II patients and prospective diagnostic experience
por: Koelzer, Viktor H, et al.
Publicado: (2017)

Update on the current opinion, status and future development of digital pathology in Switzerland in light of COVID-19
por: Koelzer, Viktor Hendrik, et al.
Publicado: (2022)

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis
por: Kobelt, Dennis, et al.
Publicado: (2021)

Tumour budding and its clinical implications in gastrointestinal cancers
por: Zlobec, Inti, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3dce3rghdieijti18b11c4g5do