Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

BACKGROUND: Controlled human malaria infection (CHMI) accelerates development of anti-malarial interventions. So far, CHMI is done by exposure of volunteers to bites of five mosquitoes carrying Plasmodium falciparum sporozoites (PfSPZ), a technique available in only a few centres worldwide. Mosquito...

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Detalles Bibliográficos
Autores principales: Mordmüller, Benjamin, Supan, Christian, Sim, Kim Lee, Gómez-Pérez, Gloria P, Ospina Salazar, Carmen Lucelly, Held, Jana, Bolte, Stefanie, Esen, Meral, Tschan, Serena, Joanny, Fanny, Lamsfus Calle, Carlos, Löhr, Sascha JZ, Lalremruata, Albert, Gunasekera, Anusha, James, Eric R, Billingsley, Peter F, Richman, Adam, Chakravarty, Sumana, Legarda, Almudena, Muñoz, Jose, Antonijoan, Rosa M, Ballester, Maria Rosa, Hoffman, Stephen L, Alonso, Pedro L, Kremsner, Peter G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371633/
https://www.ncbi.nlm.nih.gov/pubmed/25889522
http://dx.doi.org/10.1186/s12936-015-0628-0

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