Bullous pemphigoid and neurological disease: statistics from a dermatology service()

Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have report...

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Detalles Bibliográficos
Autores principales: Tarazona, Monica Jidid Mateus, Mota, Amanda Nascimento Cavalleiro de Macedo, Gripp, Alexandre Carlos, Unterstell, Natasha, Bressan, Aline Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371687/
https://www.ncbi.nlm.nih.gov/pubmed/25831008
http://dx.doi.org/10.1590/abd1806-4841.20153334
Descripción
Sumario:Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have reported an association between BP and neurological disorders (ND). Our cohort of Bullous pemphigoid and ND is the first in Brazil and showed a significantly high prevalence of neurological and/or psychiatric diseases, especially cerebrovascular accident (CVA) and dementia, in agreement with the prevalence reported in several studies published in the medical literature in recent years.

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