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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

INTRODUCTION: In early stages of Alzheimer’s disease (AD), neurofibrillary tangles (NFT) are largely restricted to the entorhinal cortex and medial temporal lobe. At later stages, when clinical symptoms generally occur, NFT involve widespread limbic and association cortices. At this point in the dis...

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Detalles Bibliográficos
Autores principales:	Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371800/ https://www.ncbi.nlm.nih.gov/pubmed/25853174 http://dx.doi.org/10.1186/s40478-015-0199-x

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