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Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment

The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Zfp335(bloto/bloto) mice exhibit a naïv...

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Detalles Bibliográficos
Autores principales:	Han, Brenda Y, Wu, Shuang, Foo, Chuan-Sheng, Horton, Robert M, Jenne, Craig N, Watson, Susan R, Whittle, Belinda, Goodnow, Chris C, Cyster, Jason G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Genes and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371841/ https://www.ncbi.nlm.nih.gov/pubmed/25343476 http://dx.doi.org/10.7554/eLife.03549

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