Cargando…

The Middle X Residue Influences Cotranslational N-Glycosylation Consensus Site Skipping

[Image: see text] Asparagine (N)-linked glycosylation is essential for efficient protein folding in the endoplasmic reticulum (ER) and anterograde trafficking through the secretory pathway. N-Glycans are attached to nascent polypeptides at consensus sites, N-X-T/S (X ≠ P), by one of two enzymatic is...

Descripción completa

Detalles Bibliográficos
Autores principales: Malaby, Heidi L. H., Kobertz, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372077/
https://www.ncbi.nlm.nih.gov/pubmed/25029371
http://dx.doi.org/10.1021/bi500681p