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Carbohydrate-Based Polymers for Immune Modulation

[Image: see text] Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact th...

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Detalles Bibliográficos
Autores principales: Lin, Kenneth, Kasko, Andrea M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372078/
https://www.ncbi.nlm.nih.gov/pubmed/25844272
http://dx.doi.org/10.1021/mz5002417
Descripción
Sumario:[Image: see text] Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact the biological interaction of carbohydrate-bearing chains with their binding partners. This viewpoint highlights synthetic advances and potential applications of carbohydrate-based polymers for immune modulation. It also offers future directions in polymer science necessary for carbohydrate polymers to fulfill their potential as immune modulators.