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Carbohydrate-Based Polymers for Immune Modulation
[Image: see text] Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372078/ https://www.ncbi.nlm.nih.gov/pubmed/25844272 http://dx.doi.org/10.1021/mz5002417 |
| _version_ | 1782363124790198272 |
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| author | Lin, Kenneth Kasko, Andrea M. |
| author_facet | Lin, Kenneth Kasko, Andrea M. |
| author_sort | Lin, Kenneth |
| collection | PubMed |
| description | [Image: see text] Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact the biological interaction of carbohydrate-bearing chains with their binding partners. This viewpoint highlights synthetic advances and potential applications of carbohydrate-based polymers for immune modulation. It also offers future directions in polymer science necessary for carbohydrate polymers to fulfill their potential as immune modulators. |
| format | Online Article Text |
| id | pubmed-4372078 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American
Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-43720782015-06-17 Carbohydrate-Based Polymers for Immune Modulation Lin, Kenneth Kasko, Andrea M. ACS Macro Lett [Image: see text] Carbohydrates play prominent roles in immune surveillance and response to infection. Multivalency, molecular weight control, and molecular architecture control are properties that polymer science is well suited to address. Each of these properties has been demonstrated to impact the biological interaction of carbohydrate-bearing chains with their binding partners. This viewpoint highlights synthetic advances and potential applications of carbohydrate-based polymers for immune modulation. It also offers future directions in polymer science necessary for carbohydrate polymers to fulfill their potential as immune modulators. American Chemical Society 2014-06-17 2014-07-15 /pmc/articles/PMC4372078/ /pubmed/25844272 http://dx.doi.org/10.1021/mz5002417 Text en Copyright © 2014 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
| spellingShingle | Lin, Kenneth Kasko, Andrea M. Carbohydrate-Based Polymers for Immune Modulation |
| title | Carbohydrate-Based Polymers for Immune Modulation |
| title_full | Carbohydrate-Based Polymers for Immune Modulation |
| title_fullStr | Carbohydrate-Based Polymers for Immune Modulation |
| title_full_unstemmed | Carbohydrate-Based Polymers for Immune Modulation |
| title_short | Carbohydrate-Based Polymers for Immune Modulation |
| title_sort | carbohydrate-based polymers for immune modulation |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372078/ https://www.ncbi.nlm.nih.gov/pubmed/25844272 http://dx.doi.org/10.1021/mz5002417 |
| work_keys_str_mv | AT linkenneth carbohydratebasedpolymersforimmunemodulation AT kaskoandream carbohydratebasedpolymersforimmunemodulation |