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Tandem Mass Spectrometry Assays of Palmitoyl Protein Thioesterase 1 and Tripeptidyl Peptidase Activity in Dried Blood Spots for the Detection of Neuronal Ceroid Lipofuscinoses in Newborns

[Image: see text] We report new substrates for quantitative enzyme activity measurements of human palmitoyl protein thioesterase (PPT1) and tripeptidyl peptidase (TPP1) in dried blood spots from newborns using tandem mass spectrometry. Deficiencies in these enzyme activities due to inborn errors of...

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Detalles Bibliográficos
Autores principales:	Barcenas, Mariana, Xue, Chang, Marushchak-Vlaskin, Tatyana, Scott, C. Ronald, Gelb, Michael H., Tureček, František
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372105/ https://www.ncbi.nlm.nih.gov/pubmed/25019629 http://dx.doi.org/10.1021/ac501994b

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