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HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells
[Image: see text] We examined the effects of isoform-specific histone deacetylase (HDAC) inhibitors on β-catenin posttranslational modifications in neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs). β-catenin is a multifunctional protein with important roles in...
Autores principales: | Iaconelli, Jonathan, Huang, Joanne H., Berkovitch, Shaunna S., Chattopadhyay, Shrikanta, Mazitschek, Ralph, Schreiber, Stuart L., Haggarty, Stephen J., Karmacharya, Rakesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372110/ https://www.ncbi.nlm.nih.gov/pubmed/25546293 http://dx.doi.org/10.1021/cb500838r |
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