Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts

[Image: see text] The combination of the N-based pincer ligand PyBOX with Pt(2+) leads to new catalysts for the enantioselective cycloisomerization of dienyl- and trienyl-ols. The mechanistic combination of electrophilic cyclization followed by rapid protodemetalation is surprising and leads to a po...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha, Gagné, Michel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372115/
https://www.ncbi.nlm.nih.gov/pubmed/25838970
http://dx.doi.org/10.1021/cs401190c
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author Nguyen, Ha
Gagné, Michel R.
author_facet Nguyen, Ha
Gagné, Michel R.
author_sort Nguyen, Ha
collection PubMed
description [Image: see text] The combination of the N-based pincer ligand PyBOX with Pt(2+) leads to new catalysts for the enantioselective cycloisomerization of dienyl- and trienyl-ols. The mechanistic combination of electrophilic cyclization followed by rapid protodemetalation is surprising and leads to a powerful construct for developing new reactions.
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spelling pubmed-43721152015-03-31 Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts Nguyen, Ha Gagné, Michel R. ACS Catal [Image: see text] The combination of the N-based pincer ligand PyBOX with Pt(2+) leads to new catalysts for the enantioselective cycloisomerization of dienyl- and trienyl-ols. The mechanistic combination of electrophilic cyclization followed by rapid protodemetalation is surprising and leads to a powerful construct for developing new reactions. American Chemical Society 2014-02-03 2014-03-07 /pmc/articles/PMC4372115/ /pubmed/25838970 http://dx.doi.org/10.1021/cs401190c Text en Copyright © 2014 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Nguyen, Ha
Gagné, Michel R.
Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title_full Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title_fullStr Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title_full_unstemmed Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title_short Enantioselective Cascade Cyclization/Protodemetalation of Polyenes with N(3)Pt(2+) Catalysts
title_sort enantioselective cascade cyclization/protodemetalation of polyenes with n(3)pt(2+) catalysts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372115/
https://www.ncbi.nlm.nih.gov/pubmed/25838970
http://dx.doi.org/10.1021/cs401190c
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